Ghoshal's career began when she won the Sa Re Ga Ma Pa contest as an adult. Her Bollywood playback singing career began with Devdas, for which she received National Film Award for Best Female Playback Singer along with Filmfare Award for Best Female Playback Singer and Filmfare RD Burman Award for New Music Talent. Since then, she has worked in more than 180 films and received four National Film Awards, four Filmfare Award for Best Female Playback Singer and four Filmfare Awards South
.As a child, she won the children's special episode of the Sa Re Ga Ma (now Sa Re Ga Ma Pa) contest on Zee TV. Kalyanji, who also judged the competition, convinced her parents to move to Mumbai.She trained with Kalyanji for 18 months and continued her classical music training with Mukta Bhide in Mumba.
Shreya Ghoshal caught the attention of director Sanjay Leela Bhansali when she participated in Sa Re Ga Ma Pa for a second time, this time as an adult. In 2000, he offered her the opportunity to be the voice of Paro, the lead female character of the film Devdas, who was portrayed by Aishwarya Rai.Ghoshal sang five songs in the film. Her performance won her the Filmfare Award for Best Female Playback Singer, as well as Filmfare's RD Burman Award for New Music Talent. She also won the National Film Award for the song "Bairi Piya"